Remenár E, Tóth J, Virágh S, Bartók I
Acta Morphol Acad Sci Hung. 1982;30(1):35-48.
The ultrastructure of perisinusoidal (PS) cells was studied in the liver of young pigs 1-28 days after birth. In immature animals these cells have long cytoplasmic processes often surrounding almost the entire sinusoid. In their close vicinity newly formed collagen filaments are found. While in the adult pig the PS cell cytoplasm is almost totally occupied by a large lipid droplet, in the young animal it contained only a few small lipid droplets, accompanied by a well-developed granular endoplasmic reticulum and Golgi-apparatus, microtubules and filaments 5-6 nm in diameter. The latter formed bundles with patchy dark areas. Findings indicate that during early postnatal development the function of PS cells is protein synthesis, perhaps for the production of reticulum fibres rather than fat or vitamin-A storage. In addition, PS cells by containing contractile elements may regulate the width of the sinusoids.
研究了出生后1至28天幼猪肝脏中窦周（PS）细胞的超微结构。在未成熟动物中，这些细胞具有长的细胞质突起，常常几乎围绕整个肝血窦。在其紧邻区域可发现新形成的胶原纤维。成年猪的PS细胞胞质几乎完全被一个大脂滴占据，而幼龄动物的PS细胞仅含有少数小脂滴，伴有发育良好的颗粒内质网和高尔基体、微管以及直径为5 - 6纳米的细丝。后者形成带有斑片状暗区的束状结构。研究结果表明，在出生后早期发育过程中，PS细胞的功能是蛋白质合成，可能是用于产生网状纤维，而非储存脂肪或维生素A。此外，PS细胞通过含有收缩元件可能调节肝血窦的宽度。
