白细胞蛋白酶抑制剂的生化与生物学特性
Biochemical and biological characteristics of leucocyte proteinase inhibitors.
作者信息
Kopitar M, Drobnic-Kosorok M, Babnik J, Brzin J, Turk V, Korbelik M, Batista U, Svetina S, Skrk J, Giraldi T, Sava G
出版信息
Adv Exp Med Biol. 1982;141:233-45. doi: 10.1007/978-1-4684-8088-7_25.
PMID:7090916
Abstract
Pig leucocytes contain inhibitors of neutral and thiol proteinases. These proteins could be isolated from post-granule supernatant fraction as well as from nuclear extract using ion exchange chromatography, gel chromatography and affinity chromatography. Inhibitors differ in molecular weight, isoelectric point, immunologically and their inhibition ability against tested enzymes.
摘要
猪白细胞含有中性和巯基蛋白酶抑制剂。这些蛋白质可以通过离子交换色谱、凝胶色谱和亲和色谱从颗粒后上清液部分以及核提取物中分离出来。抑制剂在分子量、等电点、免疫特性以及对测试酶的抑制能力方面存在差异。
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