Brandt L J, Boley S J, Mitsudo S
Am J Gastroenterol. 1982 Jun;77(6):382-6.
The clinical behavior and course of ischemic, ulcerative, and Crohn's colitis in the elderly are analyzed. Fifty-two patients with ischemic colitis, 11 with ulcerative colitis, and four with Crohn's colitis composed the study group. Patients with ischemic colitis were older and had a higher incidence of arteriosclerotic cardiovascular disease than those with inflammatory bowel disease. A potentially obstructing colonic lesion was present in 12% of those with ischemic colitis. Spontaneous rapid resolution occurred in 42% of those with ischemic colitis, but in no patient with ulcerative or Crohn's colitis. Of the 31 remaining patients with ischemic colitis, 20% had recurrent disease and 80% required operation. Almost 10% of patients with ischemic colitis died postoperatively. Of those patients with ulcerative colitis, two developed toxic dilitation, three required operation, and three died on the first admission. All patients with Crohn's colitis required operation. The prognosis for colitis in elderly patients, regardless of type, is worse than in young patients.
对老年缺血性、溃疡性和克罗恩氏结肠炎的临床行为及病程进行了分析。研究组包括52例缺血性结肠炎患者、11例溃疡性结肠炎患者和4例克罗恩氏结肠炎患者。缺血性结肠炎患者比炎症性肠病患者年龄更大，动脉硬化性心血管疾病的发病率更高。12%的缺血性结肠炎患者存在潜在的结肠梗阻性病变。42%的缺血性结肠炎患者病情自发快速缓解，但溃疡性或克罗恩氏结肠炎患者无一例如此。其余31例缺血性结肠炎患者中，20%复发，80%需要手术。近10%的缺血性结肠炎患者术后死亡。溃疡性结肠炎患者中，2例发生中毒性巨结肠，3例需要手术，3例首次入院时死亡。所有克罗恩氏结肠炎患者均需手术。老年结肠炎患者，无论何种类型，预后均比年轻患者差。
