Rosene K A, Featherstone H J, Benedetti T J
Am J Obstet Gynecol. 1982 Jun 15;143(4):405-7. doi: 10.1016/0002-9378(82)90081-3.
Two pregnant patients with a history of migraine each developed evidence of cerebral ischemia while being treated with subcutaneous terbutaline, for asthma in one case and for tocolysis in the other. The evidence for cerebral ischemia as well as the occurrence of strokes associated with pregnancy or migraine is discussed. Mechanisms by which a selective beta 2 agonist could affect cerebral vasculature are unknown. Until more is known we recommend that pregnant patients with migraine or vascular headache not be given terbutaline.
两名有偏头痛病史的孕妇在接受皮下注射特布他林治疗时均出现了脑缺血迹象，其中一例是用于治疗哮喘，另一例是用于抑制宫缩。本文讨论了脑缺血的证据以及与妊娠或偏头痛相关的中风的发生情况。选择性β2激动剂影响脑血管的机制尚不清楚。在了解更多情况之前，我们建议患有偏头痛或血管性头痛的孕妇不要使用特布他林。
