清醒猪钙稳态系统对推注钙注射的瞬态反应。

Transient response of the calcium homeostatic system of the conscious pig to bolus calcium injections.

作者信息

Járos G G, Maier H, Podzuweit T, von Gülich M, Schindler J G

出版信息

Am J Physiol. 1982 Jul;243(1):R125-30. doi: 10.1152/ajpregu.1982.243.1.R125.

DOI:10.1152/ajpregu.1982.243.1.R125

Abstract

Calcium injection in the pig elicits a fast transient response which reinstates the calcium concentration to within normal limits between 30 and 40 min after injection. Although the fate of the calcium that disappeared is not known, the present experiments eliminate the kidneys and the bone remodeling cells as the main short-term regulators. The fast response is independent of parathyroid hormone but is greatly dependent of calcitonin. Further experiments are being performed to discover the nature and site of the regulating mechanisms.

摘要

给猪注射钙会引发快速的短暂反应，该反应会在注射后30至40分钟内将钙浓度恢复到正常范围内。尽管消失的钙的去向尚不清楚，但目前的实验排除了肾脏和骨重塑细胞作为主要短期调节因子的可能性。这种快速反应独立于甲状旁腺激素，但很大程度上依赖于降钙素。正在进行进一步的实验以发现调节机制的性质和部位。