Hinds M W, Cohen H I, Kolonel L N
Am Rev Respir Dis. 1982 Jun;125(6):776-8. doi: 10.1164/arrd.1982.125.6.776.
We ascertained prior pulmonary tuberculosis infection in 211 non-Caucasian female lung cancer patients and 419 sex, race, ape, smoking history and birthplace-matched control subjects by searching the Hawaii State Tuberculosis Branch patient records. Among never-smokers we found a significant increase in risk associated with prior tuberculous infection (odds ratio, 8.2; 95% confidence limits = 1.3 to 54.4). No such association was found among smokers. Prior tuberculous infection was identified in only 5.5% of never-smoking lung cancer patients, however, suggesting that this factor is a relatively unimportant contributor to the etiologic aspects of lung cancer in persons who have never smoked.
我们通过查阅夏威夷州结核病防治部门的患者记录，确定了211名非白种女性肺癌患者以及419名在性别、种族、年龄、吸烟史和出生地相匹配的对照受试者既往有肺结核感染史。在从不吸烟者中，我们发现既往结核感染相关风险显著增加（比值比为8.2；95%置信区间为1.3至54.4）。在吸烟者中未发现此类关联。然而，仅5.5%的从不吸烟肺癌患者被发现有既往结核感染，这表明该因素在从不吸烟者肺癌病因方面的作用相对较小。
