5-S-半胱氨酰多巴胺的O-甲基化代谢
Metabolism of 5-S-cyteinyldopa by O-methylation.
作者信息
Agrup G, Falck B, Hansson C, Rorsman H, Rosengren A M, Rosengren E
出版信息
Acta Derm Venereol. 1977;57(4):309-12.
PMID:70921
Abstract
5-S-cysteinyldopa is metabolized by O-methylation on incubation with a liver extract and S-adenosyl methionine. O-methylated 5-S-cysteinyldopa isolated from melanoma urines by ion exchange and paper chromatography was identified by gas chromatography-mass spectrometry and NMR.
摘要
5-S-半胱氨酰多巴与肝提取物及S-腺苷甲硫氨酸一起温育时通过O-甲基化进行代谢。通过离子交换和纸色谱法从黑色素瘤尿液中分离得到的O-甲基化5-S-半胱氨酰多巴，经气相色谱-质谱联用仪和核磁共振波谱仪进行鉴定。
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