人类恶性黑色素瘤中游离和结合的5-S-半胱氨酰多巴及多巴
Free and bound 5-S-cysteinyldopa and dopa in human malignant melanomas.
作者信息
Agrup G, Hansson C, Rorsman H, Rosengren A M, Rosengren E
出版信息
Acta Derm Venereol. 1978;58(3):270-2.
PMID:78645
Abstract
Free dopa and 5-S-cysteinyldopa were extracted from two human melanomas. Subsequent hydrolysis of carefully washed melanoma tissue released dopa and 5-S-cysteinyldopa, indication the presence of these catechol amino acids in proteins. Cysteinyldopa-containing proteins may represent the antigens previously demonstrated in human melanomas.
摘要
从两个人类黑色素瘤中提取了游离多巴和5-S-半胱氨酰多巴。对仔细洗涤过的黑色素瘤组织进行后续水解后释放出多巴和5-S-半胱氨酰多巴，这表明这些儿茶酚氨基酸存在于蛋白质中。含半胱氨酰多巴的蛋白质可能代表了先前在人类黑色素瘤中证实的抗原。
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