复方苯乙哌啶不会导致波兰综合征。
Debendox does not cause the Poland anomaly.
作者信息
David T J
出版信息
Arch Dis Child. 1982 Jun;57(6):479-80. doi: 10.1136/adc.57.6.479.
Abstract
The suggestion that Debendox may cause the Poland anomaly is refuted by a study of the antenatal drug exposure in 46 cases of the Poland anomaly and 32 cases of isolated absence of the pectoralis major. Debendox had been prescribed in one case of the Poland anomaly and in one case of isolated pectoralis absence, but in neither was the compound given during organogenesis. In none of the 78 cases could Debendox be causally implicated.
摘要
一项针对46例波兰综合征病例和32例单纯胸大肌缺如病例的产前药物暴露研究，驳斥了关于多潘立酮可能导致波兰综合征的说法。在1例波兰综合征病例和1例单纯胸大肌缺如病例中曾开具过多潘立酮，但均不是在器官形成期给予该药物的。在这78例病例中，没有一例可以将多潘立酮认定为病因。
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引用本文的文献
1
Familial Poland anomaly.家族性波兰综合征。
J Med Genet. 1983 Apr;20(2):152-4. doi: 10.1136/jmg.20.2.152.
本文引用的文献
1
Debendox and limb reduction deformities.复方苯乙哌啶与肢体短小畸形
Med J Aust. 1981 Apr 18;1(8):417-8. doi: 10.5694/j.1326-5377.1981.tb135685.x.
2
Poland syndrome: a concept of pathogenesis based on limb bud embryology.
Birth Defects Orig Artic Ser. 1977;13(3D):103-15.
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