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低水平镉和铅对儿童认知功能的影响。

Effects of low levels of cadmium and lead on cognitive functioning in children.

作者信息

Thatcher R W, Lester M L, McAlaster R, Horst R

出版信息

Arch Environ Health. 1982 May-Jun;37(3):159-66. doi: 10.1080/00039896.1982.10667557.

DOI:10.1080/00039896.1982.10667557
PMID:7092333
Abstract

Hair cadmium and lead content were related to intelligence tests, motor impairment assessments, and school achievement scores from 149 children aged 5 to 16 yr enrolled in rural Maryland public school systems. Hair cadmium and lead were significantly correlated with both intelligence scores and school achievement scores, but not motor impairment scores. Significant relations with I.Q. were obtained after regressing out demographic factors and were observed, even in children within a normal I.Q. range. Evidence of different effects of cadmium and lead on cognitive development was obtained. Hierarchical regression analyses suggest that cadmium has a significantly stronger effect on verbal I.Q. than does lead and that lead has a stronger effect on performance I.Q. than does cadmium.

摘要

对马里兰州农村公立学校系统中149名5至16岁儿童的头发镉和铅含量与智力测试、运动障碍评估及学业成绩得分进行了研究。头发镉和铅含量与智力得分及学业成绩得分均显著相关,但与运动障碍得分无关。在排除人口统计学因素后,与智商仍存在显著关系,且在智商处于正常范围的儿童中也观察到了这种关系。获得了镉和铅对认知发展不同影响的证据。分层回归分析表明,镉对言语智商的影响显著强于铅,而铅对操作智商的影响强于镉。

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