Jajić I, Furst Z, Vuksic B
Ann Rheum Dis. 1982 Jun;41(3):237-41. doi: 10.1136/ard.41.3.237.
Nine patients (5 male and 4 female) are described with mild pain in the lumbar and thoracolumbar spine, early morning pain, morning stiffness, and moderately reduced mobility of the spine. Initial x-ray examination of the spine revealed sclerosis of one or several vertebral bodies and erosions in various parts of the vertebral bodies. In the further course of the disease squaring, sacroiliitis, and arthritis of the apophyseal joints was found. Seven of the 9 patients had the histocompatability antigen HLA B27. On the basis of these observations it is considered that 7 of these 9 patients had ankylosing spondylitis, the erosive lesions of the vertebral bodies being the first visible signs of the disease.
本文描述了9例患者(5例男性,4例女性),他们有腰及胸腰椎轻度疼痛、晨痛、晨僵以及脊柱活动度中度降低。脊柱的初始X线检查显示一个或多个椎体硬化以及椎体各部位有侵蚀。在疾病的进一步发展过程中,发现椎体呈方形、骶髂关节炎以及关节突关节关节炎。9例患者中有7例具有组织相容性抗原HLA B27。基于这些观察结果,认为这9例患者中有7例患有强直性脊柱炎,椎体的侵蚀性病变是该疾病最早可见的体征。