Danilova O A, Chernigovskaia E V
Zh Evol Biokhim Fiziol. 1989 Nov-Dec;25(6):763-8.
In 10--81-day and adult Wistar rats, neurosecretory cells were revealed which react with antisera to corticoliberin and vasopressin. Morphometric analysis of these cells in the supraoptic, paraventricular and anterior commissural nuclei shows that in the latter vasopressinergic cells develop somewhat later than in the supraoptic and paraventricular nuclei. Complete differentiation of neurosecretory cells in all the centres investigated is observed in 2-month animals. Studies were also made on the amount of corticoliberin- and vasopressinergic terminals in the external zone of the median eminence. Vasopressin-immunoreactive fibers are more numerous in young rats than in adult ones. Corticoliberin-positive neurosecretory fibers are more abundant in adult animals. Earlier development of vasopressinergic elements corresponds to a hypothesis of a more ancient origin of nonapeptidergic structures as compared to those producing liberins and statins.
在10至81日龄的幼龄和成年Wistar大鼠中，发现了与促肾上腺皮质激素释放素和血管加压素抗血清发生反应的神经分泌细胞。对视上核、室旁核和前连合核中的这些细胞进行形态计量分析表明，后一个核中血管加压素能细胞的发育比视上核和室旁核中的细胞稍晚。在2月龄动物中观察到所有研究中心的神经分泌细胞完全分化。还对正中隆起外侧区促肾上腺皮质激素释放素和血管加压素能终末的数量进行了研究。血管加压素免疫反应性纤维在幼鼠中比成年鼠中更多。促肾上腺皮质激素释放素阳性神经分泌纤维在成年动物中更为丰富。血管加压素能成分的较早发育符合这样一种假说，即与产生释放素和抑制素的结构相比，九肽能结构的起源更为古老。
