Slepecky N, Chamberlain S C
Arch Otorhinolaryngol. 1982;234(2):131-4. doi: 10.1007/BF00453618.
The distribution and polarity of actin in chinchilla cochlear hair cells was determined by decoration of actin filaments with myosin subfragment S1. Actin is present in the stereocilia above the cuticular plate and there are actin filaments randomly oriented within the cuticular plate. These results in chinchilla cochlear hair cells agree with the findings in the frog, guinea pig, and alligator lizard inner ears. In the cross-striated region at the base of the cuticular plate of inner hair cells there are actin filaments which label with S1. These decorated filaments appear closely associated with the dense bands but the thin filaments perpendicular to the dense bands appear unlabeled. The presence of actin filaments in this cross-striated region at the base of the cuticular plate supports a mechanism that has been suggested for actin-myosin mediated movement of stereocilia [10], which would cause the stereocilia of inner hair cells to fan out into the endolymph.
通过用肌球蛋白亚片段S1标记肌动蛋白丝来确定毛丝鼠耳蜗毛细胞中肌动蛋白的分布和极性。肌动蛋白存在于表皮板上方的静纤毛中，并且在表皮板内有随机取向的肌动蛋白丝。毛丝鼠耳蜗毛细胞的这些结果与青蛙、豚鼠和短吻鳄蜥蜴内耳的研究结果一致。在内毛细胞表皮板基部的横纹区域有可被S1标记的肌动蛋白丝。这些被标记的丝似乎与致密带紧密相关，但垂直于致密带的细丝似乎未被标记。表皮板基部这个横纹区域中肌动蛋白丝的存在支持了一种关于肌动蛋白-肌球蛋白介导的静纤毛运动的机制[10]，这将导致内毛细胞的静纤毛向内淋巴中展开。
