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狒狒、狗和黑长尾猴心脏血管壁中乙酰胆碱酯酶的组织化学定位。

Histochemical localization of acetylcholinesterase in the wall of cardiac blood vessels in the baboon, dog and vervet monkey.

作者信息

Pillay C V, Reid J V

出版信息

Basic Res Cardiol. 1982 Mar-Apr;77(2):213-9. doi: 10.1007/BF01908174.

DOI:10.1007/BF01908174
PMID:7092779
Abstract

Histochemical methods were used to demonstrate acetylcholinesterase in the wall of cardiac blood vessels in the baboon, dog and vervet monkey. To remove cholinesterase-containing sympathetic nerves, some of the animals were treated with guanethidine for four weeks prior to being sacrificed. In cardiac muscle from the dog and the vervet monkey, cholinergic nerves were histochemically visualized in both small and large vessels. On the other hand, in cardiac muscle from baboons, cholinergic nerves were not seen in branches of the coronary artery with diameters between 0.6 mm to 1 mm and very few fibres were seen around smaller vessels of diameter less than 0.3 mm. The few fibres seen did not appear to penetrate the media of the vessels. These results support physiological findings that the baboon coronary vasculature is not innervated by parasympathetic cholinergic nerves.

摘要

采用组织化学方法在狒狒、狗和黑长尾猴的心脏血管壁中显示乙酰胆碱酯酶。为去除含胆碱酯酶的交感神经,部分动物在处死前用胍乙啶治疗四周。在狗和黑长尾猴的心肌中,大小血管内均可通过组织化学方法观察到胆碱能神经。另一方面,在狒狒的心肌中,直径在0.6毫米至1毫米之间的冠状动脉分支中未见胆碱能神经,直径小于0.3毫米的较小血管周围仅见极少纤维。所见的极少纤维似乎并未穿透血管中层。这些结果支持了生理学研究结果,即狒狒的冠状血管系统不受副交感胆碱能神经支配。

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