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Effect of the opioid analgesic tramadol on inactivation of norepinephrine and serotonin.

作者信息

Hennies H H, Friderichs E, Wilsmann K, Floh e L

出版信息

Biochem Pharmacol. 1982 Apr 15;31(8):1654-5. doi: 10.1016/0006-2952(82)90398-7.

DOI:10.1016/0006-2952(82)90398-7
PMID:7092957
Abstract
摘要

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Effect of the opioid analgesic tramadol on inactivation of norepinephrine and serotonin.阿片类镇痛药曲马多对去甲肾上腺素和5-羟色胺失活的影响。
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Antidepressant biochemical profile of the novel bicyclic compound Wy-45,030, an ethyl cyclohexanol derivative.
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[Effect of MAO inhibitors on impeding synaptosomal withdrawal and on dopamine metabolism in rat and human brain].[单胺氧化酶抑制剂对阻止大鼠和人类大脑突触体退缩及多巴胺代谢的作用]
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Effects of the central analgesic tramadol on the uptake and release of noradrenaline and dopamine in vitro.中枢镇痛药曲马多对去甲肾上腺素和多巴胺体外摄取及释放的影响。
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Effect of acute and chronic tramadol on [3H]-5-HT uptake in rat cortical synaptosomes.急性和慢性曲马多对大鼠皮质突触体中[3H]-5-羟色胺摄取的影响。
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Mutations in monoamine oxidase (MAO) genes in mice lead to hypersensitivity to serotonin-enhancing drugs: implications for drug side effects in humans.
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Tramadol and another atypical opioid meperidine have exaggerated serotonin syndrome behavioural effects, but decreased analgesic effects, in genetically deficient serotonin transporter (SERT) mice.在基因缺陷型血清素转运体(SERT)小鼠中,曲马多和另一种非典型阿片类药物哌替啶具有夸大的血清素综合征行为效应,但镇痛效果降低。
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Effectiveness of electro-acupuncture compared to sedo-analgesics in relieving pain during shockwave lithotripsy.与镇静镇痛药相比,电针在缓解冲击波碎石术期间疼痛方面的有效性。
Urol Res. 2005 Aug;33(4):285-90. doi: 10.1007/s00240-005-0473-7. Epub 2005 Jun 22.
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[Pharmacology of tramadol].[曲马多的药理学]
Drugs. 1997;53 Suppl 2:18-24. doi: 10.2165/00003495-199700532-00006.
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Effects of the central analgesic tramadol on the uptake and release of noradrenaline and dopamine in vitro.中枢镇痛药曲马多对去甲肾上腺素和多巴胺体外摄取及释放的影响。
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