Ashby E C, Rees M, Dowding C H
Br Med J. 1978 Nov 4;2(6147):1263-4. doi: 10.1136/bmj.2.6147.1263.
Five minutes after transrectal prostatic biopsy 16 out of 21 patients were shown by blood culture to have bacteraemia. Antibiotic prophylaxis--routinely with ampicillin and metronidazole for 48 hours--prevented progression to septicaemia, and four days after the procedure all blood samples were negative. Irrespective of whether antibiotic prophylaxis is used, blood culture should be routine in all patients undergoing transrectal prostatic biopsy.
经直肠前列腺活检后5分钟，血培养显示21例患者中有16例发生菌血症。抗生素预防——常规使用氨苄西林和甲硝唑48小时——可防止进展为败血症，术后4天所有血样均为阴性。无论是否使用抗生素预防，对所有接受经直肠前列腺活检的患者进行血培养都应成为常规操作。
