Rom W N, Varley G, Lyon J L, Shopkow S
Br J Ind Med. 1982 Aug;39(3):269-72. doi: 10.1136/oem.39.3.269.
Occupational exposure to arsenic has been associated with cancer of the lung, but epidemiological studies of cancer of the lung and environmental exposure to arsenic have produced conflicting results. Case-control studies about point sources of pollution have been useful in identifying environmental hazards. This technique was used to evaluate the risk for lung cancer near a smelter in El Paso, Texas, that uses an arsenic-containing ore and has been in continuous operation since 1887. A comparison of 575 cases of lung cancer with 1490 breast and prostate controls collected from 1944 to 1973 found no significant associations with distance using 2-km concentric circles out to 20 km from the smelter.
职业性接触砷与肺癌有关,但肺癌的流行病学研究以及砷的环境暴露研究结果却相互矛盾。关于污染点源的病例对照研究在识别环境危害方面很有用。这项技术被用于评估德克萨斯州埃尔帕索市一家冶炼厂附近的肺癌风险,该厂使用含砷矿石,自1887年以来一直在持续运营。对1944年至1973年收集的575例肺癌病例与1490例乳腺癌和前列腺癌对照进行比较,结果发现,以冶炼厂为中心、半径2公里至20公里的同心圆范围内,肺癌与距离之间没有显著关联。