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一项针对西方一家大型铜冶炼厂死亡率的回顾性流行病学研究。

A retrospective epidemiological study of mortality at a large western copper smelter.

作者信息

Rencher A C, Carter M W, McKee D W

出版信息

J Occup Med. 1977 Nov;19(11):754-8.

PMID:915570
Abstract

In comparing the smelter with the mine, concentrator, and State of Utah, it was found that they were very similar in the percentage of deaths due to all causes except lung cancer; 7.0% of all deaths at the smelter were due to lung cancer compared to 2.2% for the mine, 2.2% for the concentrator, and 2.7% for the state. The excess at the smelter was statistically significant. Approximate age-adjusted death rates were obtained for various causes of death. The rates for the smelter are higher than for the mine and the state for lung cancer and for all causes combined. The average age at death for smelter workers is nearly the same as for mine employees, even for those who died of lung cancer. Smoking data was examined and there was no indication of a smoking synergism. Cumulative exposure indices for SO2, H2SO4 mist, As, Pb, and Cu were computed for each deceased smelter worker based n the length of time he worked in each of 12 major areas. Those who died of lung cancer had the highest average exposure index for all five constituents. Stack emission data showed much higher levels of As and SO2 prior to 1959.

摘要

在将冶炼厂与矿山、选矿厂以及犹他州进行比较时发现,除肺癌外,它们在各种原因导致的死亡百分比方面非常相似;冶炼厂所有死亡案例中有7.0%是由肺癌导致的,而矿山为2.2%,选矿厂为2.2%,该州为2.7%。冶炼厂的这一超额比例在统计学上具有显著意义。针对各种死因得出了大致的年龄调整死亡率。冶炼厂在肺癌以及所有死因综合方面的死亡率高于矿山和该州。冶炼厂工人的平均死亡年龄与矿山员工几乎相同,即使是那些死于肺癌的工人。对吸烟数据进行了检查,没有发现吸烟协同作用的迹象。根据每位已故冶炼厂工人在12个主要区域中每个区域的工作时长,计算了他们的二氧化硫、硫酸雾、砷、铅和铜的累积暴露指数。死于肺癌的人在所有五种成分上的平均暴露指数最高。烟囱排放数据显示,1959年之前砷和二氧化硫的水平要高得多。

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