[Content of intracellular ATP and structural state of proteins in the erythrocyte membrane].

Effects of depletion and resynthesis of intracellular ATP on the properties of human erythrocytes (deformability, osmotic fragility) and on the structural parameters of their membranes (U. V. fluorescence spectra, protein aggregation) were studied. Incubation of the erythrocytes in the absence of glucose at 37 degrees C was shown to result in a number of consequent alterations: crenating and decrease in deformability of erythrocyte cells--a change in relative contents of membrane proteins--aggregation of membrane proteins and reversible shift of their fluorescence spectra. The evidence is considered in favour of the spectra shift due to dephosphorylation of membrane proteins.