猪胰高血糖素对犬十二指肠和空肠运动的作用。
The action of porcine glucagon on the motility of the canine duodenum and jejunum.
作者信息
Evans D F, Foster G E, Hardcastle J D, Jonhson F, Wright J W
出版信息
Br J Pharmacol. 1982 Jun;76(2):245-52. doi: 10.1111/j.1476-5381.1982.tb09213.x.
Abstract
1 Intravenous bolus doses of porcine glucagon of 0.001-0.05 mg kg-1 caused intense stimulation of the duodenum and jejunum of the dog. 2 Intravenous infusion of porcine glucagon at 0.025-0.05 mg kg-1 h-1 caused similar stimulation. In both cases the stimulation was phasic in nature. 3 Stimulation of the duodenum and jejunum following glucagon was accompanied by a decrease in frequency of the intestinal basic electrical rhythm (BER). No change was seen in the intervals between successive periods of phase III motor activity.
摘要
- 静脉注射剂量为0.001 - 0.05毫克/千克的猪胰高血糖素，可引起犬十二指肠和空肠的强烈刺激。2. 以0.025 - 0.05毫克/千克·小时的速度静脉输注猪胰高血糖素，也会产生类似的刺激。在这两种情况下，刺激本质上都是阶段性的。3. 胰高血糖素引起的十二指肠和空肠刺激伴随着肠道基本电节律（BER）频率的降低。连续III期运动活动之间的间隔未见变化。
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