Kantner R M, Kirby M L
Brain Res. 1982 Apr 29;238(2):451-6. doi: 10.1016/0006-8993(82)90122-6.
Two-day and 15-day-old offspring of capsaicin-pretreated Wistar rats were given subcutaneous injections of a 5% formalin solution to the dorsal aspect of the right forepaw. One hour after injection, acid phosphatase activity of the substantia gelatinosa of formalin/capsaicin cervical sections was significantly greater bilaterally than in saline/capsaicin 15-day-old animals. In 2-day-old animals the formalin/control right cervical sections had significantly higher acid phosphatase activity than saline/control. These results are further support for a direct functional relation between activity in the substantia gelatinosa and chemogenic pain stimulus.
给经辣椒素预处理的Wistar大鼠2日龄和15日龄的子代右前爪背侧皮下注射5%的福尔马林溶液。注射后1小时，福尔马林/辣椒素处理组双侧颈段脊髓胶状质的酸性磷酸酶活性显著高于生理盐水/辣椒素处理的15日龄动物。在2日龄动物中，福尔马林/对照组右颈段脊髓切片的酸性磷酸酶活性显著高于生理盐水/对照组。这些结果进一步支持了脊髓胶状质活性与化学性疼痛刺激之间存在直接功能关系。
