Mathew T
Cancer. 1982 Aug 1;50(3):507-14. doi: 10.1002/1097-0142(19820801)50:3<507::aid-cncr2820500322>3.0.co;2-o.
A case of an alveolar soft part sarcoma was studied electron microscopically. This showed tumor cells separated by external lamina that incorporated desmosome-like structures. Well defined basal lamina separated several cells from underlying endothelial cells by a zone of tissue composed predominantly of fibrous long-spacing collagen. A unique finding was the presence within several tumor cells of well defined myelin sheaths and myelinated axons. Apart from various other intracellular organelles some of the cells contained closely aggregated fine filamentous structures: the so-called "angulate bodies." All these findings are interpreted as evidence for a tumor showing marked Schwann cell differentiation, and therefore, it is suggested that alveolar soft part sarcoma is histogenetically a neoplasm of the neural crest.
对1例肺泡软组织肉瘤进行了电镜研究。结果显示，肿瘤细胞被包含桥粒样结构的外板分隔。明确的基底膜通过一个主要由纤维性长间距胶原组成的组织区域将几个细胞与下层内皮细胞分隔开。一个独特的发现是，在几个肿瘤细胞内存在明确的髓鞘和有髓轴突。除了各种其他细胞内细胞器外，一些细胞还含有紧密聚集的细丝状结构：即所谓的“角形体”。所有这些发现都被解释为肿瘤具有明显施万细胞分化的证据，因此，有人提出肺泡软组织肉瘤在组织发生学上是一种神经嵴肿瘤。
