Wei T H, Tseng P T, Lee W H, Chou C H
Zhonghua Min Guo Wei Sheng Wu Ji Mian Yi Xue Za Zhi. 1982 May;15(2):132-9.
The mass pre-control survey was done in fall semester 1978 by both methods that Kato's thick smear for helminthic infection and cellophane tape perianal swab for pinworm infection. There are about 19,000 primary school children and around 5,000 kindergarten children in Suan-yuan District, being the subjects. The helminthic positive rates (%) obtained were 5.18 and 3.81, respectively. The rates for pinworm were found 28.68% former and 29.00% for the latter. Drug was given to the egg-positive persons after mass examination, in each semester, for three consecutive years. Two broad-spectrum anthelmintics, pyrantel pamoate and mebendazole were used. The children who harbored Ascaris, hookworm or pinworm were given pyrantel tablet as a single dose of 10 mg/kg body weight, and whipworm positives were given a standard course of 100 mg of mebendazole twice daily for three days. After three-year operation, in accordance with the results of examination in Spring semester 1981, the egg positive rates were sharply dropped to 0.56% for the primary school children and 0.50% for the kindergarten. The pinworm infection rates for the above-mentioned group were also reduced to 13.05% and 18.68%, respectively.
1978年秋季学期采用两种方法进行了大规模预控调查,即采用加藤厚涂片法检测蠕虫感染,采用透明胶带肛周拭子法检测蛲虫感染。蒜园地区约有19000名小学生和5000名幼儿园儿童作为研究对象。蠕虫感染阳性率分别为5.18%和3.81%。蛲虫感染率前者为28.68%,后者为29.00%。在大规模检查后的每个学期,连续三年对虫卵阳性者给药。使用了两种广谱驱虫药,即噻嘧啶和甲苯咪唑。感染蛔虫、钩虫或蛲虫的儿童单次服用噻嘧啶片,剂量为10mg/kg体重,鞭虫阳性者则给予标准疗程的甲苯咪唑,每日两次,每次100mg,连服三天。经过三年的防治,根据1981年春季学期的检查结果,小学生的虫卵阳性率急剧降至0.56%,幼儿园儿童降至0.50%。上述群体的蛲虫感染率也分别降至13.05%和18.68%。