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苯妥英钠与苯巴比妥对远场听觉及体感诱发电位峰间期影响的比较。

Comparison of phenytoin and phenobarbital effects on far-field auditory and somatosensory evoked potential interpeak latencies.

作者信息

Green J B, Walcoff M R, Lucke J F

出版信息

Epilepsia. 1982 Aug;23(4):417-21. doi: 10.1111/j.1528-1157.1982.tb05428.x.

DOI:10.1111/j.1528-1157.1982.tb05428.x
PMID:7094907
Abstract

Far-field somatosensory and auditory evoked potential (EP) interpeak latencies were measured in normal controls, epileptics not receiving medications, and epileptics receiving phenytoin, phenobarbital, or both. Phenytoin, but no phenobarbital, was associated with a prolongation of EP interpeak latencies at serum level concentrations over 20 micrograms/ml. Neither carbamazepine nor primidone in smaller series were associated with prolongation of EP interpeak latencies.

摘要

在正常对照组、未接受药物治疗的癫痫患者以及接受苯妥英钠、苯巴比妥或两者联合治疗的癫痫患者中，测量了远场体感和听觉诱发电位（EP）的峰间潜伏期。当血清水平浓度超过20微克/毫升时，苯妥英钠（而非苯巴比妥）与EP峰间潜伏期延长有关。在较小样本量的研究中，卡马西平和扑米酮均未与EP峰间潜伏期延长相关。

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Comparison of phenytoin and phenobarbital effects on far-field auditory and somatosensory evoked potential interpeak latencies.苯妥英钠与苯巴比妥对远场听觉及体感诱发电位峰间期影响的比较。
Epilepsia. 1982 Aug;23(4):417-21. doi: 10.1111/j.1528-1157.1982.tb05428.x.
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The influence of seizure type on the efficacy of plasma concentrations of phenytoin, phenobarbital, and carbamazepine.癫痫发作类型对苯妥英钠、苯巴比妥和卡马西平血药浓度疗效的影响。
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Effects of carbamazepine and valproate on brainstem auditory evoked potentials in epileptic children.卡马西平和丙戊酸盐对癫痫患儿脑干听觉诱发电位的影响。
Childs Nerv Syst. 1995 Aug;11(8):474-7. doi: 10.1007/BF00334968.
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Brain-stem auditory evoked potentials in the fragile X syndrome.脆性X综合征中的脑干听觉诱发电位
Am J Hum Genet. 1989 Dec;45(6):977-9.