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铁从肠道吸收进入血液的研究:大鼠性别与时间相关性研究

Absorption of iron from gut into blood: sex- and time-related studies in rats.

作者信息

Richter G W, Lee Y H

出版信息

Experientia. 1982 May 15;38(5):583-5. doi: 10.1007/BF02327061.

DOI:10.1007/BF02327061
PMID:7095092
Abstract

As judged from 2-h blood level curves, adult female rats absorbed more FeII per cm2 of gross duodenal mucosa than adult male rats. By contrast, the 2-h blood level curves per cm2 of mucosa of proximal jejunum did not differ significantly in male and female rats although in both sexes, iron was absorbed more efficiently from the duodenum.

摘要

从2小时血药浓度曲线判断,成年雌性大鼠每平方厘米十二指肠黏膜吸收的二价铁比成年雄性大鼠多。相比之下,尽管两性中十二指肠对铁的吸收更有效,但雄性和雌性大鼠每平方厘米空肠近端黏膜的2小时血药浓度曲线并无显著差异。

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引用本文的文献

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Intersection of Iron and Copper Metabolism in the Mammalian Intestine and Liver.铁与铜代谢在哺乳动物肠道和肝脏中的交汇。
Compr Physiol. 2018 Sep 14;8(4):1433-1461. doi: 10.1002/cphy.c170045.

本文引用的文献

1
FURTHER EVIDENCE OF SEX VARIATION IN THE UTILIZATION OF IRON BY ANEMIC RATS.贫血大鼠铁利用中性别差异的进一步证据。
Science. 1940 Feb 9;91(2354):146-7. doi: 10.1126/science.91.2354.146.
2
STUDIES ON IRON ABSORPTION. INTESTINAL REGULATORY MECHANISMS.铁吸收的研究。肠道调节机制。
J Clin Invest. 1964 Jul;43(7):1433-42. doi: 10.1172/JCI105019.
3
Studies on intermediary iron metabolism. X. The influence of age and sex on the storage of supplemental dietary iron in the rat.铁代谢中间过程的研究。十、年龄和性别对大鼠膳食补充铁储存的影响。
Aust J Exp Biol Med Sci. 1957 Apr;35(2):123-9.
4
Ascorbic acid chelates in iron absorption: a role for hydrochloric acid and bile.抗坏血酸在铁吸收中的螯合作用:盐酸和胆汁的作用。
Gastroenterology. 1968 Jul;55(1):35-45.
5
Sex difference in the ferritin content of rat liver.大鼠肝脏中铁蛋白含量的性别差异。
Biochim Biophys Acta. 1970 Dec 22;221(3):583-92. doi: 10.1016/0005-2795(70)90230-8.
6
Mechanism of sex difference in rat tissue iron stores.
Biochim Biophys Acta. 1973 Jan 24;297(1):70-80. doi: 10.1016/0304-4165(73)90050-0.
7
Iron absorption in the rat: the search for possible intestinal mucosal carriers.大鼠体内的铁吸收:寻找可能的肠黏膜载体。
Br J Haematol. 1976 Oct;34(2):237-50. doi: 10.1111/j.1365-2141.1976.tb00194.x.
8
Ferritin in rat kidneys with specific lesions due to a single dose of lead.单剂量铅导致特定损伤的大鼠肾脏中的铁蛋白
Am J Pathol. 1979 Mar;94(3):483-96.
9
Ferritin: structure, biosynthesis, and role in iron metabolism.
Physiol Rev. 1978 Apr;58(2):317-96. doi: 10.1152/physrev.1978.58.2.317.