• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

乙酰胆碱乙酰水解酶（E.C. 3.1.1.7）抑制对大鼠不同脑区中对，对'-滴滴涕蓄积的影响。

Effect of acetylcholine acetyl-hydrolase (E.C. 3.1.1.7) inhibition on the accumulation of pp' DDT in various brain regions of rats.

作者信息

Matin M A, Agarwal R

出版信息

Experientia. 1982 May 15;38(5):607-8. doi: 10.1007/BF02327076.

DOI:10.1007/BF02327076
PMID:7095102
Abstract

The concentration of pp' DDT given intraperitoneally in rats was determined in different brain regions. Maximum accumulation of pp' DDT was found in the corpus striatum, followed by cerebellum and cerebral cortex in that order; following pretreatment with paraoxon the concentrations of pp' DDT were increased in all brain regions studied

摘要

测定了大鼠腹腔注射pp’-滴滴涕（pp’-DDT）后在不同脑区中的浓度。发现pp’-DDT在纹状体中的蓄积量最大，其次依次为小脑和大脑皮层；用对氧磷预处理后，在所研究的所有脑区中pp’-DDT的浓度均升高。

相似文献

1
Effect of acetylcholine acetyl-hydrolase (E.C. 3.1.1.7) inhibition on the accumulation of pp' DDT in various brain regions of rats.乙酰胆碱乙酰水解酶（E.C. 3.1.1.7）抑制对大鼠不同脑区中对，对'-滴滴涕蓄积的影响。
Experientia. 1982 May 15;38(5):607-8. doi: 10.1007/BF02327076.
2
Effect of paraoxon on cholinesterase activity in certain brain regions of diabetic rats.对氧磷对糖尿病大鼠某些脑区胆碱酯酶活性的影响。
Eur J Pharmacol. 1974 Nov;29(1):168-70. doi: 10.1016/0014-2999(74)90185-x.
3
A study of the effects of certain barbiturates on the level of striatal acetylcholine and convulsions in 1,1,1-trichloro-2,2-bis(4'-chlorophenyl) ethane (pp' DDT) treated rats.关于某些巴比妥类药物对1,1,1-三氯-2,2-双（4'-氯苯基）乙烷（滴滴涕）处理的大鼠纹状体乙酰胆碱水平和惊厥影响的研究。
Pharmacol Res Commun. 1979 Apr;11(4):371-7. doi: 10.1016/s0031-6989(79)80080-6.
4
Investigation of the effect of chlorophenothane and certain chemically related compounds on the cerebral gamma-aminobutyric acid contents in rats.氯苯乙烷及某些化学相关化合物对大鼠脑内γ-氨基丁酸含量影响的研究。
Pol J Pharmacol Pharm. 1978 Jul-Aug;30(4):469-74.
5
Serum concentrations of DDT and DDE among malaria control workers in the Amazon region.亚马逊地区疟疾防治工作者的血清 DDT 和 DDE 浓度。
J Occup Health. 2011;53(2):115-22. doi: 10.1539/joh.o10026. Epub 2011 Jan 11.
6
[Study on the analytical method for organochlorine pesticide residue using gas chromatography-mass spectrometry].气相色谱-质谱联用测定有机氯农药残留量的分析方法研究
Wei Sheng Yan Jiu. 1998 Nov 30;27(6):425-8.
7
Distribution of DDT, DDD, and DDE in tissues of neonatal rats and in milk and other tissues of mother rats chronically exposed to DDT.
Toxicol Appl Pharmacol. 1971 Apr;18(4):907-16. doi: 10.1016/0041-008x(71)90238-9.
8
Relationship between choline availability and acetylcholine synthesis in discrete regions of rat brain.大鼠脑不同区域胆碱可用性与乙酰胆碱合成之间的关系。
J Neurochem. 1979 Mar;32(3):961-7. doi: 10.1111/j.1471-4159.1979.tb04581.x.
9
Effects of pentobarbital on the regulation of acetylcholine content and release in different regions of rat brain.戊巴比妥对大鼠脑不同区域乙酰胆碱含量及释放调节的影响。
Biochem Pharmacol. 1977 Apr 1;26(7):609-15. doi: 10.1016/0006-2952(77)90033-8.
10
Effect of externally added carnitine on the synthesis of acetylcholine in rat cerebral cortex cells.外源性添加肉碱对大鼠大脑皮层细胞中乙酰胆碱合成的影响。
Neurochem Int. 1995 Jun;26(6):635-41. doi: 10.1016/0197-0186(94)00162-n.

本文引用的文献

1
Increased Permeability of the Hemoencephalic Barrier Produced by Physostigmine and Acetylcholine.毒扁豆碱和乙酰胆碱引起的血脑屏障通透性增加。
Science. 1949 Sep 2;110(2853):237. doi: 10.1126/science.110.2853.237.
2
The relationship between cholinesterase activity and brain permeability.
J Pharmacol Exp Ther. 1951 May;102(1):1-4.
3
Pharmacology of organophosphorus cholinesterase inhibitors.有机磷胆碱酯酶抑制剂的药理学
Pharmacol Rev. 1959 Sep;11:567-688.
4
POISONING BY DDT: RELATION BETWEEN CLINICAL SIGNS AND CONCENTRATION IN RAT BRAIN.滴滴涕中毒：大鼠脑内临床体征与浓度之间的关系
Science. 1963 Dec 13;142(3598):1474-6. doi: 10.1126/science.142.3598.1474.
5
A new and rapid colorimetric determination of acetylcholinesterase activity.一种新的快速比色法测定乙酰胆碱酯酶活性。
Biochem Pharmacol. 1961 Jul;7:88-95. doi: 10.1016/0006-2952(61)90145-9.
6
The occurrence, distribution and physiological role of catecholamines in the nervous system.儿茶酚胺在神经系统中的发生、分布及生理作用。
Pharmacol Rev. 1959 Jun;11(2, Part 2):490-3.
7
Regional studies of catecholamines in the rat brain. I. The disposition of [3H]norepinephrine, [3H]dopamine and [3H]dopa in various regions of the brain.大鼠脑中儿茶酚胺的区域研究。I. [3H]去甲肾上腺素、[3H]多巴胺和[3H]多巴在脑不同区域的分布。
J Neurochem. 1966 Aug;13(8):655-69. doi: 10.1111/j.1471-4159.1966.tb09873.x.
8
Acetyl- and butyrylcholinesterase activity of selected brain areas in developing rats after neonatal x-irradiation.新生大鼠经X射线照射后发育过程中选定脑区的乙酰胆碱酯酶和丁酰胆碱酯酶活性
J Neurochem. 1966 Feb;13(2):75-84. doi: 10.1111/j.1471-4159.1966.tb03334.x.
9
The synthesis and storage of acetylcholine in the striatum.纹状体内乙酰胆碱的合成与储存。
J Neurochem. 1966 Jun;13(6):515-24. doi: 10.1111/j.1471-4159.1966.tb09866.x.
10
Acetyl- and pseudocholinesterase activities in sympathetic ganglia of rats.大鼠交感神经节中的乙酰胆碱酯酶和假性胆碱酯酶活性
J Neurochem. 1968 Oct;15(10):1121-30. doi: 10.1111/j.1471-4159.1968.tb06829.x.