[含吡啶和噻二唑单元的开链及环状体系二芳基硫醚的抗真菌作用]
[Antimycotic effect of diaryl sulfides with open chains and ring systems containing pyridine and thiadiazole units].
作者信息
Bottino F, Russo F, Blandino G
出版信息
Farmaco Sci. 1982 May;37(5):298-303.
PMID:7095142
Abstract
A series of diaryl sulfides containing pyridine or 1,3,4-thiadiazole units was prepared. All the products were tested in vitro against the following strains: Candida albicans, Candida parapsilosis, Candida tropicalis, Cryptococcus neoformas and Trichophyton rubrum. Some of the compounds synthesized showed marked antifungal activity.
摘要
制备了一系列含有吡啶或1,3,4-噻二唑单元的二芳基硫化物。所有产物均针对以下菌株进行了体外测试：白色念珠菌、近平滑念珠菌、热带念珠菌、新型隐球菌和红色毛癣菌。合成的一些化合物显示出显著的抗真菌活性。
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