Taneda Y, Watanabe H
Dev Comp Immunol. 1982 Spring;6(2):243-52. doi: 10.1016/s0145-305x(82)80007-4.
Fusion experiments with three colonies (AC-BC-BD) by Tanaka and Watanabe indicated that the mixture of blood from two nonfusible colonies induced a "nonfusion" reaction (NFR)-like responses. Thus, artificial mixture of the blood from two nonfusible colonies is expected to result in NFR-like reactions. The present study deals with an in vivo bioassay using syngeneic and allogeneic blood injections. Syngeneic injection of whole blood induced no response, while allogeneic injection of whole blood induced inflammatory responses indicating recognition of allogeneic tissue. Syngeneic injection of blood plasma or blood cells induced no response. On the other hand, allogeneic injection of blood cells resulted in a response similar to that of whole blood injections. Allogeneic blood plasma induced only weak responses. It is hypothesized that NFR is initiated by the mutual interaction between blood cells and blood humoral factor(s).
田中与渡边对三个菌落（AC - BC - BD）进行的融合实验表明，来自两个不可融合菌落的血液混合物会引发类似“非融合”反应（NFR）的应答。因此，预计来自两个不可融合菌落的血液人工混合会导致类似NFR的反应。本研究涉及使用同基因和异基因血液注射的体内生物测定。同基因全血注射未引发反应，而异基因全血注射引发了炎症反应，表明对异基因组织的识别。同基因注射血浆或血细胞未引发反应。另一方面，异基因注射血细胞导致的反应与全血注射相似。异基因血浆仅引发微弱反应。据推测，NFR是由血细胞与血液体液因子之间的相互作用引发的。
