使用静脉注射133Xe洗脱法进行脑血流分析的两种优化算法的比较
Comparison of two optimizing algorithms for cerebral blood flow analysis using the intravenous 133Xe wash-out method.
作者信息
Pitänen M A, Kuikka J T, Kiiliäinen H, Macey D J
出版信息
Int J Biomed Comput. 1982 May;13(3):213-20. doi: 10.1016/0020-7101(82)90040-x.
The analysis of cerebral blood flow data using intravenous injection and inhalation of 133Xe requires a correction for the arterial recirculation. With a multi-exponential transfer function a problem exists in estimating the non-linear parameters. In this paper conventional two-compartmental blood flow indices from the intravenous 133Xe clearance method are calculated using Marquardt and variable metric optimizing algorithms. Close agreement was found between these two methods in that they yield similar values for the cerebral transfer function.
使用静脉注射和吸入133Xe分析脑血流数据需要对动脉再循环进行校正。对于多指数传递函数，在估计非线性参数时存在问题。本文使用Marquardt算法和变尺度优化算法计算了静脉注射133Xe清除法的传统双室血流指数。发现这两种方法之间有密切的一致性，因为它们得出的脑传递函数值相似。
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