Hoffman B F
J Clin Psychiatry. 1982 Aug;43(8):338-9.
A patient is described who was diagnosed in an outpatient department as having paranoid psychosis and later chronic schizophrenia, which was treated with chlorpromazine. Two years later, the patient was admitted to hospital because of increasing confusion, disorganization, and numerous manic symptoms. Physical examination and serologic examination of blood and CSF confirmed the diagnosis of general paresis. Correct treatment led to the eventual discontinuation of neuroleptics and the cessation of paranoid and manic symptoms.
描述了一名患者，其在门诊被诊断为偏执型精神病，后来又被诊断为慢性精神分裂症，接受了氯丙嗪治疗。两年后，患者因意识混乱加剧、行为紊乱以及出现大量躁狂症状而入院。体格检查以及血液和脑脊液的血清学检查确诊为全身性麻痹性痴呆。正确的治疗最终导致停用抗精神病药物，偏执和躁狂症状也随之消失。
