Witkowski J A, Parish L C
J Am Acad Dermatol. 1982 Jun;6(6):1014-21. doi: 10.1016/s0190-9622(82)70085-4.
The histologic studies of the decubitus ulcer spectrum, which include blanchable erythema, nonblanchable erythema, decubitus dermatitis, decubitus ulcer, and the black eschar/gangrene reveal a dynamic process. The initial change occurs in the vessels of the papillary dermis. This is followed by necrosis of skin structures. The eschar/gangrene represents a full-thickness defect due either to prolonged ischemia and anoxemia or a sudden large vessel occlusion caused by shearing injury.
对褥疮溃疡谱系的组织学研究，包括可褪色红斑、不可褪色红斑、褥疮性皮炎、褥疮溃疡以及黑色焦痂/坏疽，揭示了一个动态过程。最初的变化发生在乳头层真皮的血管中。随后是皮肤结构的坏死。焦痂/坏疽代表全层缺损，这是由于长期缺血和缺氧或剪切伤导致的突然大血管闭塞所致。
