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不同物种乳汁中游离肌醇的测定及其在大鼠(褐家鼠)乳汁中的来源

Estimation of free myo-inositol in milks of various species and its source in milk of rats (Rattus norvegicus).

作者信息

Byun S M, Jenness R

出版信息

J Dairy Sci. 1982 Apr;65(4):531-6. doi: 10.3168/jds.S0022-0302(82)82230-3.

DOI:10.3168/jds.S0022-0302(82)82230-3
PMID:7096723
Abstract

Free myo-inositol content of milk of rats and other rodents fed standard laboratory chow is 80 mg/100 g as compared to about 4 mg/100 g for cow milk. Feeding experiments with graded amounts of myo-inositol demonstrated that the myo-inositol content of milk is strongly influenced by dietary intake. Radioactivity from either [carbon-14] glucose or [hydrogen-3] myo-inositol injected intraperitoneally was incorporated rapidly into milk myo-inositol. Thus, both mammary biosynthesis and active transport contribute to the high myo-inositol in rat milk, but the latter is quantitatively the more important.

摘要

与每100克约含4毫克肌醇的牛奶相比,以标准实验室饲料喂养的大鼠和其他啮齿动物的乳汁中游离肌醇含量为每100克80毫克。用不同剂量的肌醇进行的喂养实验表明,乳汁中的肌醇含量受饮食摄入量的强烈影响。腹腔注射的[碳-14]葡萄糖或[氢-3]肌醇的放射性迅速掺入乳汁肌醇中。因此,乳腺生物合成和主动转运都对大鼠乳汁中高含量的肌醇有贡献,但后者在数量上更为重要。

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1
Estimation of free myo-inositol in milks of various species and its source in milk of rats (Rattus norvegicus).不同物种乳汁中游离肌醇的测定及其在大鼠(褐家鼠)乳汁中的来源
J Dairy Sci. 1982 Apr;65(4):531-6. doi: 10.3168/jds.S0022-0302(82)82230-3.
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Both myo-inositol to chiro-inositol epimerase activities and chiro-inositol to myo-inositol ratios are decreased in tissues of GK type 2 diabetic rats compared to Wistar controls.与Wistar对照大鼠相比,GK 2型糖尿病大鼠组织中的肌醇向手性肌醇表异构酶活性以及手性肌醇与肌醇的比例均降低。
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Characterization and tissue distribution of 6-O-beta-D-galactopyranosyl myo-inositol in the rat.大鼠体内6-O-β-D-吡喃半乳糖基肌醇的表征及组织分布
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Simultaneous determination of myo-inositol and scyllo-inositol by MEKC as a rapid monitoring tool for inositol levels.采用胶束电动毛细管色谱法同时测定肌醇和 scyllo -肌醇,作为肌醇水平的快速监测工具。
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