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Elevated serum thyroxine concentration in patients receiving "replacement" doses of levothyroxine.

作者信息

Ingbar J C, Borges M, Iflah S, Kleinmann R E, Braverman L E, Ingbar S H

出版信息

J Endocrinol Invest. 1982 Mar-Apr;5(2):77-85. doi: 10.1007/BF03350495.

DOI:10.1007/BF03350495
PMID:7096921
Abstract
摘要

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1
Elevated serum thyroxine concentration in patients receiving "replacement" doses of levothyroxine.接受左甲状腺素“替代”剂量治疗的患者血清甲状腺素浓度升高。
J Endocrinol Invest. 1982 Mar-Apr;5(2):77-85. doi: 10.1007/BF03350495.
2
[Internal medicine therapy of thyroid gland diseases].[甲状腺疾病的内科治疗]
Med Klin. 1970 May 8;65(19):923-8.
3
Thyroid hormones.甲状腺激素
Br Med J. 1969 May 31;2(5656):561-2.
4
[Thyroid gland therapy with novothyral].[用左旋甲状腺素进行甲状腺治疗]
Med Klin. 1969 May 23;64(21):973-5.
5
Evaluation of the measurement of reverse T3 in suspected thyroid disease.疑似甲状腺疾病中反三碘甲状腺原氨酸测量的评估。
Med Lab Sci. 1983 Jul;40(3):235-42.
6
[Relation of serum levels of reverse triiodothyronine, thyroxine and triiodothyronine in selected thyroid diseases].[特定甲状腺疾病中血清反三碘甲状腺原氨酸、甲状腺素和三碘甲状腺原氨酸水平的关系]
Endokrynol Pol. 1986;37(5):211-8.
7
Relevance of increased serum thyroxine concentrations associated with normal serum triiodothyronine values in hypothyroid patients receiving thyroxine: a case for "tissue thyrotoxicosis".接受甲状腺素治疗的甲状腺功能减退患者中血清甲状腺素浓度升高与血清三碘甲状腺原氨酸值正常相关的意义：“组织甲状腺毒症”的实例
Br Med J (Clin Res Ed). 1984 Dec 15;289(6459):1645-7. doi: 10.1136/bmj.289.6459.1645.
8
Diagnosis and treatment of hypothyroidism in TSH deficiency compared to primary thyroid disease: pituitary patients are at risk of under-replacement with levothyroxine.与原发性甲状腺疾病相比，TSH 缺乏症的甲状腺功能减退症的诊断和治疗：垂体患者接受左甲状腺素替代治疗不足的风险更高。
Clin Endocrinol (Oxf). 2011 Jun;74(6):744-9. doi: 10.1111/j.1365-2265.2011.03984.x.
9
The management of thyroid diseases.甲状腺疾病的管理
Trans Med Soc Lond. 1972;88:34-9.
10
Biologic blood markers reflecting thyroid hormone effect at peripheral tissue level in patients receiving levothyroxine replacement for hypothyroidism.在接受左甲状腺素替代治疗甲状腺功能减退症的患者中，反映外周组织水平甲状腺激素作用的生物血标志物。
Acta Med Hung. 1991;48(1-2):33-43.

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Resistance to thyroid hormone due to a novel mutation in the thyroid beta receptor () gene coexisting with autoimmune thyroid disease-A case report.甲状腺β受体（）基因新突变导致的甲状腺激素抵抗与自身免疫性甲状腺疾病并存——病例报告
Front Genet. 2023 Apr 4;14:1051042. doi: 10.3389/fgene.2023.1051042. eCollection 2023.
2
Serum Thyrotropin and Triiodothyronine Levels in Levothyroxine-treated Patients.左旋甲状腺素治疗患者的血清促甲状腺素和三碘甲状腺原氨酸水平。
J Clin Endocrinol Metab. 2023 May 17;108(6):e258-e266. doi: 10.1210/clinem/dgac725.
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Individualized Therapy for Hypothyroidism: Is T4 Enough for Everyone?

本文引用的文献

1
Changes in basal metabolism, serumprotein-bound iodine, and cholesterol during treatment of hypothyroidism with oral thyroid and L-thyroxine sodium.口服甲状腺片和左甲状腺素钠治疗甲状腺功能减退症期间基础代谢、血清蛋白结合碘和胆固醇的变化。
Br Med J. 1952 Mar 22;1(4759):624-8. doi: 10.1136/bmj.1.4759.624.
2
The effectiveness of triiodothyronine or thyroxine administered orally in the treatment of myxedema.口服三碘甲状腺原氨酸或甲状腺素治疗黏液性水肿的有效性。
J Clin Endocrinol Metab. 1955 Mar;15(3):285-96. doi: 10.1210/jcem-15-3-285.
3
THYROID THERAPY OF MYXEDEMA: A COMPARISON OF VARIOUS AGENTS WITH A NOTE ON THE COMPOSITION OF THYROID SECRETION IN MAN.
甲状腺功能减退症的个体化治疗：T4 对所有人都足够吗？
J Clin Endocrinol Metab. 2020 Sep 1;105(9):e3090-104. doi: 10.1210/clinem/dgaa430.
4
Resistance to thyroid hormone.对甲状腺激素的抵抗
Rev Endocr Metab Disord. 2000 Jan;1(1-2):97-108. doi: 10.1023/a:1010072605757.
5
Relevance of increased serum thyroxine concentrations associated with normal serum triiodothyronine values in hypothyroid patients receiving thyroxine: a case for "tissue thyrotoxicosis".接受甲状腺素治疗的甲状腺功能减退患者中血清甲状腺素浓度升高与血清三碘甲状腺原氨酸值正常相关的意义：“组织甲状腺毒症”的实例
Br Med J (Clin Res Ed). 1984 Dec 15;289(6459):1645-7. doi: 10.1136/bmj.289.6459.1645.
6
Euthyroid hyperthyroxinemia.甲状腺功能正常的甲状腺素血症
J Endocrinol Invest. 1983 Dec;6(6):493-505. doi: 10.1007/BF03348351.
7
'Tissue thyrotoxicosis'.组织性甲状腺毒症
Br Med J (Clin Res Ed). 1985 Feb 2;290(6465):393-4. doi: 10.1136/bmj.290.6465.393-c.
8
Suppression of peripheral blood natural killer cell activity by excess thyroid hormone.过量甲状腺激素对外周血自然杀伤细胞活性的抑制作用。
J Clin Invest. 1987 Feb;79(2):404-8. doi: 10.1172/JCI112826.
9
Euthyroid hyperthyroxinaemia.甲状腺功能正常的甲状腺素血症
J R Soc Med. 1988 Jun;81(6):369.
10
Thyroxine uptake by human hepatoma cells from serum of patients submitted to long-term thyroxine suppressive therapy.长期接受甲状腺素抑制治疗患者血清中甲状腺素被人肝癌细胞摄取的情况。
J Endocrinol Invest. 1988 Oct;11(9):629-35. doi: 10.1007/BF03350199.
黏液性水肿的甲状腺疗法：多种药物的比较及关于人类甲状腺分泌物成分的注释
Ann Intern Med. 1964 Jan;60:79-87. doi: 10.7326/0003-4819-60-1-79.
4
Equivalence of thyroid preparations.甲状腺制剂的等效性。
JAMA. 1980 Sep 5;244(10):1095.
5
Transient elevation of serum thyroid hormone concentration after initiation of replacement therapy in myxedema.黏液性水肿患者开始替代治疗后血清甲状腺激素浓度的短暂升高。
Ann Intern Med. 1980 Apr;92(4):491-5. doi: 10.7326/0003-4819-92-4-491.
6
Nonequality of brand name thyroxine preparations.品牌甲状腺素制剂的非等效性。
JAMA. 1980;243(8):733. doi: 10.1001/jama.243.8.733b.
7
Series on pharmacology in practice. 5. Thyroid hormones.实用药理学系列。5. 甲状腺激素。
Mayo Clin Proc. 1980 Jan;55(1):33-44.
8
Suppression of thyrotropin (h-TSH) in serums of patients with myxedema of varying etiology treated with thyroid hormones.甲状腺激素治疗不同病因黏液性水肿患者血清中促甲状腺激素（h-TSH）的抑制情况。
N Engl J Med. 1971 Sep 2;285(10):529-33. doi: 10.1056/NEJM197109022851001.
9
Conversion of thyroxine (T4) to triiodothyronine (T3) in athyreotic human subjects.甲状腺切除的人体受试者中甲状腺素（T4）向三碘甲状腺原氨酸（T3）的转化。
J Clin Invest. 1970 May;49(5):855-64. doi: 10.1172/JCI106304.
10
Replacement dosage of L-thyroxine in hypothyroidism. A re-evaluation.甲状腺功能减退症中左甲状腺素的替代剂量。重新评估。
N Engl J Med. 1974 Mar 7;290(10):529-33. doi: 10.1056/NEJM197403072901001.