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酗酒在接受治疗的阿片类药物成瘾者中的意义。

The significance of alcoholism in treated opiate addicts.

作者信息

Rounsaville B J, Weissman M M, Kleber H D

出版信息

J Nerv Ment Dis. 1982 Aug;170(8):479-88. doi: 10.1097/00005053-198208000-00007.

Abstract

This paper presents an evaluation of clinical characteristics of opiate addicts who also have a current or past history of alcoholism diagnosed according to Research Diagnostic Criteria. Based on data derived from a survey of 533 treated opiate addicts, the following findings were obtained. First, alcoholism in treated opiate addicts was found to be a common problem occurring at rates far exceeding those in the surrounding community in all demographic groups. Second, regarding the sequence of alcoholism and opiate addiction, most alcoholic addicts in this sample had alcohol problems before developing a drug use disorder or seeking treatment for opiate addiction. Third, entrance into treatment did not appear to lead to either increased or decreased alcohol abuse, and alcohol abuse while in treatment usually took place in those who had a history of alcohol problems. Fourth, when compared with nonalcoholic addicts, alcoholic addicts had fewer assets and more liabilities including a more disruptive childhood history, heavier history of legal problems and polydrug abuse, more severe problems with social functioning, and higher rates of psychiatric disorders. Fifth, despite these liabilities follow-up findings 6 months after seeking treatment indicate that alcoholism was of little prognostic significance in relationship to treatment outcome.

摘要

本文对根据研究诊断标准被诊断为目前或既往有酒精中毒史的阿片类成瘾者的临床特征进行了评估。基于对533名接受治疗的阿片类成瘾者的调查数据,得出了以下研究结果。首先,在接受治疗的阿片类成瘾者中,酒精中毒是一个普遍存在的问题,在所有人口统计学群体中的发生率远远超过周边社区。其次,关于酒精中毒和阿片类成瘾的先后顺序,该样本中的大多数酒精成瘾者在出现药物使用障碍或寻求阿片类成瘾治疗之前就有酒精问题。第三,开始治疗似乎并未导致酒精滥用增加或减少,且治疗期间的酒精滥用通常发生在有酒精问题病史的人身上。第四,与非酒精成瘾的成瘾者相比,酒精成瘾的成瘾者资产较少、负债较多,包括童年经历更具破坏性、法律问题和多药滥用史更严重、社会功能问题更严重以及精神障碍发生率更高。第五,尽管存在这些不利因素,但寻求治疗6个月后的随访结果表明,酒精中毒对治疗结果的预后意义不大。

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