Poduslo S E, Miller K, Zoller S
J Neurol Sci. 1982 Jun;54(3):395-400. doi: 10.1016/0022-510x(82)90202-7.
Oligodendroglia were isolated from human multiple sclerosis (MS) brain obtained at autopsy. The cells were placed in culture and assessed for functions associated with normal oligodendroglia. The oligodendroglia from MS tissue were able to incorporate radiolabeled substrate into the lipids found in brain, including cerebrosides. They also produced whorls of membrane lamellae, adjacent to the cell soma, while in culture. In these respects the oligodendroglia from affected tissue were able to function normally.
少突胶质细胞取自尸检获得的人类多发性硬化症（MS）脑部。将这些细胞置于培养环境中，并评估其与正常少突胶质细胞相关的功能。来自MS组织的少突胶质细胞能够将放射性标记的底物整合到脑部发现的脂质中，包括脑苷脂。在培养过程中，它们还会在细胞体附近产生膜片层的漩涡。在这些方面，来自病变组织的少突胶质细胞能够正常发挥功能。
