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使用无蛋白饮食评估不同体型成年犬的内源性氮输出。

Assessment of endogenous nitrogen output in adult dogs of contrasting size using a protein-free diet.

作者信息

Kendall P T, Blaza S E, Holme D W

出版信息

J Nutr. 1982 Jul;112(7):1281-6. doi: 10.1093/jn/112.7.1281.

DOI:10.1093/jn/112.7.1281
PMID:7097347
Abstract

The purpose of the work was to assess endogenous nitrogen output in dogs of widely contrasting mature body size and genotype. Fecal and urinary nitrogen excretion was measured during 14-day metabolic periods in 25 adult dogs of body-weight range 2.8-51.0 kg fed a protein-free, semipurified diet. Endogenous nitrogen excretion was assumed from day 8 after introduction of the protein-free diet and was measured during the final 7 days of each period. Mean (+/- SEM) endogenous urinary nitrogen (EUN), metabolic fecal nitrogen (MFN), and total endogenous nitrogen (TEN) outputs were 210 +/- 9, 63 +/- 3 and 273 +/- 9 mg/kg 0.75 per day. There were no significant effect of either sex or body weight on the magnitude of EUN, MFN or TEN outputs, however, EUN output was positively and significantly (P less than 0.02) correlated (r = 0.50) with percentage body-weight loss during the metabolic period. The mean values obtained for endogenous nitrogen output in adult dogs agreed closely with previous estimates in the literature for dogs exhibiting a narrower range (8.3-16.7 kg) of mature body weight.

摘要

这项工作的目的是评估成熟体型和基因型差异很大的犬只的内源性氮输出。在14天的代谢期内,对25只体重范围为2.8 - 51.0 kg的成年犬进行测量,这些犬只喂食无蛋白的半纯化日粮,测量其粪便和尿液中的氮排泄量。无蛋白日粮引入后第8天开始计算内源性氮排泄量,并在每个时期的最后7天进行测量。平均(±标准误)内源性尿氮(EUN)、代谢性粪氮(MFN)和总内源性氮(TEN)输出量分别为每天210±9、63±3和273±9 mg/kg 0.75。性别和体重对EUN、MFN或TEN输出量的大小均无显著影响,然而,EUN输出量与代谢期内体重减轻百分比呈正相关且具有显著性(P < 0.02)(r = 0.50)。成年犬内源性氮输出的平均值与文献中先前对成熟体重范围较窄(8.3 - 16.7 kg)的犬只的估计值非常接近。

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