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采用无蛋白饮食和回归技术研究成年家猫内源性氮代谢产物的尿排泄情况。

Urinary excretion of endogenous nitrogen metabolites in adult domestic cats using a protein-free diet and the regression technique.

作者信息

Hendriks W H, Moughan P J, Tarttelin M F

机构信息

Department of Animal Science, Massey University, Palmerston North, New Zealand.

出版信息

J Nutr. 1997 Apr;127(4):623-9. doi: 10.1093/jn/127.4.623.

DOI:10.1093/jn/127.4.623
PMID:9109614
Abstract

The study was designed to determine urinary excretions of endogenous total, urea, ammonia and creatinine nitrogen in adult domestic cats. Endogenous urinary nitrogen metabolite excretions were determined by feeding adult cats a protein-free diet for 10 d or by regression to zero protein intake of the urinary nitrogen metabolite excretions of adult cats fed four levels of dietary protein. The mean (+/- SEM) endogenous total, urea and ammonia nitrogen excretions for the cats fed the protein-free diet were 360 (+/- 11.3), 243 (+/- 8.8) and 27.6 (+/- 1.06) mg x kg body weight(-0.75) x d(-1), respectively. Estimates of 316 (+/- 53.9), 232 (+/- 43.4) and 33.7 (+/- 5.68) mg x kg body weight(-0.75) x d(-1), respectively, were obtained using the regression technique. The differences in results between the two techniques were not statistically significant. Daily excretions of creatinine nitrogen were not significantly (P = 0.64) different between the protein-free and regression technique (mean +/- SEM, 14.4 +/- 0.49 and 15.9 +/- 1.05 mg/kg body weight(0.75), respectively). The endogenous urinary total and urea nitrogen excretion of adult domestic cats is higher than values for other mammals such as humans, dogs, rats and pigs.

摘要

本研究旨在测定成年家猫内源性总氮、尿素氮、氨氮和肌酐氮的尿排泄量。通过给成年猫喂食无蛋白饮食10天,或根据喂食四种不同蛋白质水平日粮的成年猫尿氮代谢产物排泄量回归至零蛋白摄入量来测定内源性尿氮代谢产物排泄量。喂食无蛋白饮食的猫的平均(±标准误)内源性总氮、尿素氮和氨氮排泄量分别为360(±11.3)、243(±8.8)和27.6(±1.06)mg·kg体重(-0.75)·d(-1)。使用回归技术分别得到的估计值为316(±53.9)、232(±43.4)和33.7(±5.68)mg·kg体重(-0.75)·d(-1)。两种技术结果的差异无统计学意义。无蛋白饮食组和回归技术组之间肌酐氮的日排泄量差异不显著(P = 0.64)(平均±标准误分别为14.4±0.49和15.9±1.05mg/kg体重(0.75))。成年家猫内源性尿总氮和尿素氮排泄量高于人类、犬、大鼠和猪等其他哺乳动物的值。

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