• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Use of dipole moment as a parameter in drug-receptor interaction and quantitative structure-activity relationship studies.

作者信息

Lien E J, Guo Z R, Li R L, Su C T

出版信息

J Pharm Sci. 1982 Jun;71(6):641-55. doi: 10.1002/jps.2600710611.

DOI:10.1002/jps.2600710611
PMID:7097526
Abstract
摘要

相似文献

1
Use of dipole moment as a parameter in drug-receptor interaction and quantitative structure-activity relationship studies.
J Pharm Sci. 1982 Jun;71(6):641-55. doi: 10.1002/jps.2600710611.
2
[Theoretical aspects of the quantitative study of the chemical structure-biological action relationship].
Eksp Med Morfol. 1979;18(2):61-8.
3
[Theoretical investigations of interactions between drugs and models of receptor sites, 3: induced fit interactions of verapamil derivatives].[药物与受体位点模型间相互作用的理论研究，3：维拉帕米衍生物的诱导契合相互作用]
Arch Pharm (Weinheim). 1983;316(2):154-60. doi: 10.1002/ardp.19833160212.
4
Recognition and activation mechanisms on the LSD/serotonin receptor: the molecular basis of structure activity relationships.LSD/血清素受体的识别与激活机制：构效关系的分子基础
NIDA Res Monogr. 1978(22):333-58.
5
Conformational study of lysergic acid derivatives in relation to their hallucinogenic and antiserotonin activities.麦角酸衍生物与其致幻和抗血清素活性相关的构象研究。
NIDA Res Monogr. 1978(22):374-407.
6
Aquatic invertebrates: model systems for study of receptor activation and evolution of receptor proteins.水生无脊椎动物：用于研究受体激活及受体蛋白进化的模型系统。
Annu Rev Pharmacol Toxicol. 1977;17:243-58. doi: 10.1146/annurev.pa.17.040177.001331.
7
Quantitative structure-activity relationship by distance geometry: quinazolines as dihydrofolate reductase inhibitors.基于距离几何的定量构效关系：喹唑啉类作为二氢叶酸还原酶抑制剂
J Med Chem. 1982 Aug;25(8):892-9. doi: 10.1021/jm00350a003.
8
Molecular requirements for recognition at glucoreceptor for insulin release.胰岛素释放糖受体识别的分子要求。
Mol Pharmacol. 1979 Sep;16(2):361-8.
9
Commentary: The receptor concept in evolution.评论：进化中的受体概念。
Biochem Pharmacol. 1977 May 15;26(10):913-8. doi: 10.1016/0006-2952(77)90465-8.
10
Structure and function of snake venom curarimimetic neurotoxins.蛇毒类箭毒样神经毒素的结构与功能
Mol Pharmacol. 1978 Jul;14(4):710-6.

引用本文的文献

1
Modeling the functionalized genistein-hyoscyamine derivatives.对功能化染料木黄酮-莨菪碱衍生物进行建模。
Sci Rep. 2025 May 13;15(1):16662. doi: 10.1038/s41598-025-00371-1.
2
Synthesis and DNA binding studies of novel triazine-isatin hybrids: experimental and computational insights.新型三嗪-异吲哚酮杂化物的合成与DNA结合研究：实验与计算见解
RSC Adv. 2025 Mar 18;15(11):8443-8455. doi: 10.1039/d5ra00899a. eCollection 2025 Mar 17.
3
Synthesis, and evaluation of amide derivatives as prospective antimicrobial and antileishmanial agents.
酰胺衍生物作为潜在抗菌和抗利什曼原虫剂的合成与评价
Future Med Chem. 2025 Apr;17(7):789-802. doi: 10.1080/17568919.2025.2479419. Epub 2025 Mar 17.
4
New Active Ingredients for Sustainable Modern Chemical Crop Protection in Agriculture.用于农业可持续现代化学作物保护的新型活性成分。
ChemSusChem. 2025 Jan 14;18(2):e202401042. doi: 10.1002/cssc.202401042. Epub 2024 Oct 7.
5
Chemical Synthesis and Structure-Activity Relationship Studies of the Coagulation Factor Xa Inhibitor Tick Anticoagulant Peptide from the Hematophagous Parasite .吸血寄生虫凝血因子Xa抑制剂蜱抗凝肽的化学合成及构效关系研究
Biomimetics (Basel). 2024 Aug 12;9(8):485. doi: 10.3390/biomimetics9080485.
6
In vitro antimicrobial, anticancer evaluation, and in silico studies of mannopyranoside analogs against bacterial and fungal proteins: Acylation leads to improved antimicrobial activity.吡喃甘露糖苷类似物对细菌和真菌蛋白质的体外抗菌、抗癌评估及计算机模拟研究：酰化作用可提高抗菌活性。
Saudi Pharm J. 2024 Jun;32(6):102093. doi: 10.1016/j.jsps.2024.102093. Epub 2024 Apr 30.
7
Modification of ibuprofen to improve the medicinal effect; structural, biological, and toxicological study.布洛芬的改性以提高药效；结构、生物学及毒理学研究。
Heliyon. 2024 Mar 5;10(5):e27371. doi: 10.1016/j.heliyon.2024.e27371. eCollection 2024 Mar 15.
8
Exploring Cinnamoyl-Substituted Mannopyranosides: Synthesis, Evaluation of Antimicrobial Properties, and Molecular Docking Studies Targeting H5N1 Influenza A Virus.探索肉桂酰取代甘露吡喃糖苷：合成、抗菌性能评价及针对 H5N1 流感 A 病毒的分子对接研究。
Molecules. 2023 Dec 7;28(24):8001. doi: 10.3390/molecules28248001.
9
Pharmacokinetics, Molecular Docking and Molecular Dynamics Simulation Studies of Nucleoside Analogs for Drug Discovery- A Mini Review.核苷类似物的药代动力学、分子对接和分子动力学模拟研究——综述
Mini Rev Med Chem. 2024;24(11):1070-1088. doi: 10.2174/0113895575258033231024073521.
10
Synthesis of a novel hydrazone-based compound applied as a fluorescence turn-on chemosensor for iron(iii) and a colorimetric sensor for copper(ii) with antimicrobial, DFT and molecular docking studies.一种新型腙基化合物的合成及其作为铁（III）荧光开启化学传感器和铜（II）比色传感器的应用，并进行了抗菌、密度泛函理论（DFT）和分子对接研究。
RSC Adv. 2023 Aug 9;13(34):23819-23828. doi: 10.1039/d3ra04364a. eCollection 2023 Aug 4.