Onetti C M, Gutiérrez E, Hliba E, Aguirre C R
J Rheumatol. 1982 Mar-Apr;9(2):229-38.
Synoviorthesis was performed in 217 joints from 111 patients suffering from different stages of rheumatoid arthritis (RA). 32P-colloidal chromic phosphate was employed, with an average dose from 6 mCi for large joints (knees) to 0.3 mCi for small peripheral joints such as average dose from 6 mCi for large joints (knees) to 0.3 mCi for small peripheral joints such as the MCP or PIP joints. Satisfactory clinical results were observed in 84% of the cases and no significant side effects resulted after a follow-up period from 1 to 10 years. Striking effects after treatment were observed through histopathological studies (light and electron microscopy) and the use of contrast arthrography. We concluded that radioactive synovectomy with 32P-chromate is a very useful method for the local treatment of RA.
对111例处于不同阶段类风湿性关节炎（RA）患者的217个关节进行了滑膜切除术。使用了32P-胶体磷酸铬，大关节（膝关节）的平均剂量为6毫居里，小的外周关节如掌指关节或近端指间关节的平均剂量为0.3毫居里。84%的病例观察到了满意的临床效果，在1至10年的随访期后未产生明显副作用。通过组织病理学研究（光学和电子显微镜）以及关节造影观察到了治疗后的显著效果。我们得出结论，用32P-铬酸盐进行放射性滑膜切除是局部治疗RA的一种非常有用的方法。
