Weiss J, Shark W, Fishbein M, Kaplan L, Peter T, Klinenberg J R, Mandel W
J Rheumatol. 1982 Mar-Apr;9(2):299-302.
Life-threatening cardiac abnormalities in polymyositis (PM) patients may result from myocardial inflammation, fibrosis, or another disease process. Few procedures have reliably identified the pathologic basis for these abnormalities. We report a patient with PM, severe congestive cardiomyopathy, and life-threatening ventricular arrhythmias in whom an endomyocardial biopsy was done. The histopathological findings of fibrosis without inflammation, which were confirmed at autopsy, facilitated the decision to treat the patient symptomatically without intensification of antiinflammatory therapy. Endomyocardial biopsy may be a useful technique to determine the exact nature of serious cardiac abnormalities in PM patients so that appropriate therapy may be given.
多发性肌炎（PM）患者危及生命的心脏异常可能源于心肌炎症、纤维化或其他疾病过程。很少有检查能可靠地确定这些异常的病理基础。我们报告了一名患有PM、严重充血性心肌病和危及生命的室性心律失常的患者，该患者接受了心内膜心肌活检。尸检证实的无炎症纤维化的组织病理学发现，促使医生决定在不强化抗炎治疗的情况下对患者进行对症治疗。心内膜心肌活检可能是一种有用的技术，可用于确定PM患者严重心脏异常的确切性质，从而给予适当的治疗。
