Farrerons-Co J, Farrerons Velasco M, Vives Puiggros J, García Calderón P A
Clin Allergy. 1978 Sep;8(5):463-9. doi: 10.1111/j.1365-2222.1978.tb01497.x.
Abnormally high levels of IgE are produced in various diseases, including atopic eczema, and a functional decrease in the T-lymphocyte population occurs at the same time. T-cell function has been studied in a group of asthma patients with high, normal and low IgE levels and in a control group. T-cell function appears to be reduced in asthmatic patients with high concentrations of IgE when skin tests are performed with Candida antigen (P less than 0.05). There was also a decline in the lymphocyte transformation tests with candida antigen in autologous serum (P less than 0.05), although not in foetal calf serum. The responses to in vivo tests with streptokinase-streptodornase were normal, as was the response of the lymphocytes to PHA.
在包括特应性皮炎在内的多种疾病中，会产生异常高水平的免疫球蛋白E（IgE），同时T淋巴细胞数量会出现功能性减少。对一组IgE水平高、正常和低的哮喘患者以及一个对照组进行了T细胞功能研究。当用白色念珠菌抗原进行皮肤试验时，IgE浓度高的哮喘患者的T细胞功能似乎降低（P小于0.05）。在自体血清中用白色念珠菌抗原进行淋巴细胞转化试验时也出现了下降（P小于0.05），但在胎牛血清中未出现下降。对链激酶-链道酶进行体内试验的反应正常，淋巴细胞对植物血凝素（PHA）的反应也正常。
