Carlson R E, Dolphin D, Bernstein M
Clin Chem. 1978 Nov;24(11):2009-12.
Analysis of stool specimens from a patient with familial coproporphyria by high-performance liquid chromatography revealed that 112 microgram per gram of dry feces (14% of the total porphyrin present) was copper coproporphyrin. Examination of stool specimens from other patients with this disease confirmed the presence of significant amounts of both copper coproporphyrin and coproporphyrin. Further investigation showed that the copper coproporphyrin was probably formed by a nonenzymic incorporation of copper by the coproporphyrin in either the bile or feces.
通过高效液相色谱法对一名家族性粪卟啉病患者的粪便标本进行分析，结果显示每克干粪便中含112微克铜粪卟啉（占总卟啉量的14%）。对其他患有该病的患者的粪便标本进行检查，证实存在大量的铜粪卟啉和粪卟啉。进一步研究表明，铜粪卟啉可能是由粪卟啉在胆汁或粪便中通过非酶促方式结合铜而形成的。
