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麻风病睾丸受累的临床病理研究

Clinico-pathological study of testicular involvement in leprosy.

作者信息

Kumar B, Raina A, Kaur S, Dash R J, Samuel E, Datta B N

出版信息

Lepr India. 1982 Jan;54(1):48-55.

PMID:7098442
Abstract

Twenty five patients of lepromatous leprosy were studied clinically and histopathologically for testicular involvement. Testicular pain or swelling was the commonest complaint (68%) followed by sterility (28%) and impotence (4%). Reduced testicular size associated with soft feel was observed in 76% patients. Gynaecomastia was present in 36% and altered sexual hair pattern in 24%. Eleven out of sixteen (69%) patients had oligo/azoospermia. Out of the twenty testicular biopsies 15 (75%) had definite histological evidence of leprous pathology, irrespective of testicular size, semen picture and clinical signs and symptoms. One out of three epididymal biopsies showed minimal changes. Histopathological changes varied markedly, it was not possible to categorize these into vascular, interstitial and obliterative phases.

摘要

对25例瘤型麻风患者的睾丸受累情况进行了临床和组织病理学研究。睾丸疼痛或肿胀是最常见的主诉(68%),其次是不育(28%)和阳痿(4%)。76%的患者观察到睾丸体积减小且质地变软。36%的患者出现乳腺增生,24%的患者出现性毛模式改变。16例患者中有11例(69%)存在少精子症/无精子症。在20例睾丸活检中,15例(75%)有明确的麻风病理组织学证据,与睾丸大小、精液情况及临床体征和症状无关。3例附睾活检中有1例显示轻微改变。组织病理学变化差异很大,无法将其分为血管、间质和闭塞期。

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