Laabs W A, May E, Richter K D, Höhling H J, Althoff J, Quint P, Hansjürgens A
Langenbecks Arch Chir. 1982;356(4):231-41. doi: 10.1007/BF01263122.
In the course of supplementary physical and chemical investigations of the influence of Dynamic Interferential Current (DIC) on bone healing 24 black-head sheep were subjected to transversal osteotomy of the radius. After an instable osteosynthesis the site was exposed to repeated therapy with DIC of varying mA intensity. (Methodological details are described in part I). DIC therapy resulted in altering the temperatures in the treated tissue, dependent on the mA intensity. Further associations were verified between DIC intensity and the occurrence of hydroxyprolin, and amino acid specific collagen, which also reflected increased calcifying activity. Measurement of the calcium and phosphorus levels in the regenerated (newly forming) bone tissue documented full mineralization in the DIC-treated animals at a much earlier date than in the untreated controls that had undergone similar operations. Whether DIC specifically stimulates osteogenesis within "healing" bones is still unclear.
在对动态干扰电流(DIC)对骨愈合影响的补充物理和化学研究过程中,对24只黑头羊进行了桡骨横向截骨术。在不稳定的骨合成后,该部位接受了不同毫安强度的DIC重复治疗。(方法学细节在第一部分描述)。DIC治疗导致治疗组织中的温度发生变化,这取决于毫安强度。进一步证实了DIC强度与羟脯氨酸以及氨基酸特异性胶原蛋白的出现之间的关联,这也反映了钙化活性的增加。对再生(新形成)骨组织中钙和磷水平的测量表明,接受DIC治疗的动物的骨组织完全矿化的时间比接受类似手术的未治疗对照组要早得多。DIC是否能特异性刺激“愈合”骨骼中的成骨作用仍不清楚。