Characteristic molar ratios of magnesium, carbon dioxide, calcium and phosphorus in the mineralizing fracture callus and predentine.

From fracture callus in different stages of mineralization the contents of Mg, CO2, Ca and P were determined and compared with those found in predentine. It was found that the Mg- and CO2-contents are high in relation to Ca and P values during the prestages and early stages of mineralization. These relatively high Mg- and CO2-values are connected with high Mg/Ca, Mg/P, CO2/Ca and CO2/P ratios which strongly decrease with the increasing degree of mineralization. These results seem to be part of a general controlling mechanism of the calcification.