Newton D F, Mansbach C M
Clin Chim Acta. 1978 Oct 16;89(2):331-9. doi: 10.1016/0009-8981(78)90332-7.
beta-[14C]Sitosterol was evaluated for its usefulness as a nonabsorbable marker of lipid absorption in intubation studies. A liquid meal, including [3H]triolein as a marker of absorbable lipid, was used. The beta-sitosterol was shown to remain well mixed with triolein in the gastric antrum, validating its suitability for this type of study. In small bowel fluid, the beta-sitosterol was shown to partition into the aqueous phase in proportion to triolein and its hydrolysis products. With this system, lipid absorption was shown to take place chiefly in the jejunum in normal individuals.
在插管研究中，对β-[14C]谷甾醇作为脂质吸收的不可吸收标记物的效用进行了评估。使用了一种液体餐，其中包括[3H]三油酸甘油酯作为可吸收脂质的标记物。结果表明，β-谷甾醇在胃窦中与三油酸甘油酯充分混合，证明其适用于此类研究。在小肠液中，β-谷甾醇按比例分配到水相中，与三油酸甘油酯及其水解产物相关。通过该系统，正常个体的脂质吸收主要发生在空肠。
