Delamere N A, Paterson C A
Ophthalmic Res. 1982;14(3):230-40. doi: 10.1159/000265197.
Net changes in the levels of lens calcium, magnesium, sodium, potassium, and water content were determined following exposure in vitro to iodoacetate, ouabain, lanthanum, cyanide, quercetin and cold temperature. The lens calcium content rose following inhibition of lens metabolism but did not change following specific inhibition of the sodium pump. The data revealed that regulation of the lens calcium balance is largely independent of lens sodium and potassium content. A greater increase in lens sodium content upon iodoacetate treatment vs. ouabain treatment is discussed in relation to the elevation of lens calcium.
在体外分别暴露于碘乙酸盐、哇巴因、镧、氰化物、槲皮素和低温后，测定晶状体钙、镁、钠、钾水平及含水量的净变化。抑制晶状体代谢后，晶状体钙含量升高，但特异性抑制钠泵后，钙含量未发生变化。数据显示，晶状体钙平衡的调节在很大程度上独立于晶状体钠和钾的含量。结合晶状体钙含量的升高，讨论了碘乙酸盐处理与哇巴因处理相比，晶状体钠含量增加更多的情况。
