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遗传性肥胖的 Zucker 大鼠的饮食模式:重新审视

Meal patterns in the genetically obese Zucker rat: a reexamination.

作者信息

Castonguay T W, Upton D E, Leung P M, Stern J S

出版信息

Physiol Behav. 1982 May;28(5):911-6. doi: 10.1016/0031-9384(82)90213-x.

DOI:10.1016/0031-9384(82)90213-x
PMID:7100292
Abstract

The meal patterns of four obese and four lean female Zucker rats were analyzed using five different intermeal interval definitions in combination with four meal size definitions. Results from these 20 analyses revealed that obese rats typically initiate fewer but larger meals than their lean littermates. However, these general findings were not always observed with the use of particular combinations of intermeal interval and minimum meal size definitions. Their interaction between meal pattern analysis parameters and rats genotype led to a second series of statistical analyses. Results from these procedures revealed that unlike the "nibble-eat" pattern of intake that characterizes lean rats, obese rats seem to initiate three classes of meals; the very small meal, the typical meal, and the "super-meal". It is suggested that the analysis of the meal patterns of Zucker rats incorporate relatively large minimum meal size definition with at least two intermeal interval definitions.

摘要

使用五种不同的餐间间隔定义并结合四种餐量定义,对四只肥胖雌性和四只瘦雌性Zucker大鼠的进食模式进行了分析。这20项分析的结果显示,肥胖大鼠通常比同窝瘦鼠开始进食的次数少但餐量大。然而,在使用特定的餐间间隔和最小餐量定义组合时,并非总能观察到这些一般结果。餐食模式分析参数与大鼠基因型之间的相互作用导致了另一系列统计分析。这些程序的结果显示,与以“小口进食”为特征的瘦鼠进食模式不同,肥胖大鼠似乎开始出现三类餐食;非常小的餐食、典型餐食和“超大餐食”。建议对Zucker大鼠的餐食模式分析采用相对较大的最小餐量定义以及至少两种餐间间隔定义。

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