Matsuki H, Kasuga H, Sugita M, Osaka F, Yokoyama H
Tokai J Exp Clin Med. 1982 Mar;7(2):271-8.
A number of studies has suggested that urinary hydroxyproline can be used as an index of collagen metabolism and urinary hydroxyproline excretion is closely related to growth hormone. This report is a cohort study to demonstrate the relationship between the urinary hydroxyproline: creatinine ratio and growth rate for four years. The pattern of increased urinary hydroxyproline: creatinine ratio in adolescence appeared to be closely ralated to the general pattern of growth rate measured in school children. In has been shown that the urinary hydroxyproline: creatinine ratio is the most suitable index of the growth rate.
多项研究表明，尿羟脯氨酸可作为胶原蛋白代谢的指标，且尿羟脯氨酸排泄与生长激素密切相关。本报告是一项队列研究，旨在证明尿羟脯氨酸与肌酐比值和四年生长速率之间的关系。青少年尿羟脯氨酸与肌酐比值增加的模式似乎与在校儿童测量的生长速率总体模式密切相关。研究表明，尿羟脯氨酸与肌酐比值是生长速率最合适的指标。
