Nath N, Fang C T, Dodd R Y
Transfusion. 1982 Jul-Aug;22(4):300-1. doi: 10.1046/j.1537-2995.1982.22482251213.x.
Eight percent of blood donors were found to have antibodies to hepatitis B surface antigen when tested by radioimmunoassay using commercial test kits. Four percent of positive reactions proved nonspecific when tested by the neutralization test using pooled surface antigen. The risks in relying solely on the reactivity in commercial-kit suggested that the specificity of the assay must be confirmed.
使用商业检测试剂盒通过放射免疫测定法检测时,发现8%的献血者有乙肝表面抗原抗体。使用混合表面抗原通过中和试验检测时,4%的阳性反应被证明是非特异性的。仅依赖商业试剂盒中的反应性所带来的风险表明,该检测方法的特异性必须得到确认。